Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation

Figure 1 Thymoquinone affects the viability of LoVo colon cancer cells. To explore the effect of thymoquinone (TQ) on the viability of human LoVo colon cancer cells, we first treated LoVo cells with various concentrations (2.5, 5, 7.5, 10 and 20 μmol/L) of TQ for 24 h and subsequently measured cell viability by MTT assay. The results showed a significant reduction of cell viability of approximately 60% following treatment (20 μmol/L) for 24 h. Each value represents the mean ± SE. ^aP < 0.05; ^bP < 0.01.