Post-transplant lymphoproliferative disorder after liver transplantation: Incidence, long-term survival and impact of serum tacrolimus level

Table 1 Baseline characteristics of patients

	Pediatrics	Adults	Overall
Number	40	13	53
Mean age in years	5.05 ± 4.43	42 ± 13.39	14.11 ± 17.71
Sex, male/female	23/17	10/3	33/20
Allograft
Living donor	28	0	28
Deceased donor	12	13	25
Presenting sign and symptoms
LAP	18	9	27
Fever	13	1	14
Abdominal pain	15	3	18
Diarrhea	5	0	5
Weight loss	0	1	1
Cough and dyspnea	1	0	1
Bowel obstruction	1	0	1
Unilateral weakness	1	0	1
Underlying liver disease
HBV cirrhosis	0	5	5
Cryptogenic cirrhosis	0	2	2
PSC	0	2	2
HCV cirrhosis	0	1	1
AIH	2	1	3
Wilson’s disease	1	0	1
PFIC	5	0	5
Crigler-Najjar syndrome	8	0	8
Biliary atresia	12	0	12
Tyrosinemia	10	0	10
Budd-Chiari syndrome	1	1	2
Liver metastasis	0	1	1
Neonatal hepatitis	1	0	1
Immunosuppressive regimen
Prednisolone	39	12	49
Tacrolimus	36	10	46
Mycophenolate mofetil	15	11	26
Cyclosporine	1	4	5
Sirolimus	35	8	43

AIH: Autoimmune hepatitis; LAP: Lymphadenopathy; HBV: Hepatitis B virus; HCV: Hepatitis C virus; PFIC: Progressive familial intrahepatic cholestasis; PSC: Primary sclerosing cholangitis.