Effect of toll-like receptor 3 agonist poly I:C on intestinal mucosa and epithelial barrier function in mouse models of acute colitis

Figure 1 Effect of poly I:C administration on dextran sulfate sodium-induced acute colitis. A: The percentage of body weight change assessed daily during 1 to 8 d observation; B: Change in the disease activity index that was comprised of body weight loss, stool consistency and occult blood; C: Representative photographs of colon obtained after monitoring clinical development of colitis for 8 d; D: Quantitative analysis of the length of the colon; E: Macroscopic score inflammation assessed; F: Histological scores of the colon tissues; G: Representative photographs of HE staining of colon tissues (Magnifications, × 200). Data are expressed as mean ± SD. ^bP < 0.01 vs control group; ^dP < 0.01 vs model group.