How to improve patient satisfaction during midazolam sedation for gastrointestinal endoscopy?

Table 1 Baseline characteristics of patients according to procedure group n (%)

	EGD (n = 167)	Colonoscopy (n = 167)	Combined group1 (n = 122)	P value
Sex				0.099
Male	71 (42.5)	89 (53.3)	64 (52.5)
Female	96 (57.5)	78 (46.7)	58 (47.5)
Age (yr)				0.878
≤ 50	43 (25.7)	44 (26.3)	29 (76.2)
> 50	124 (74.3)	123 (73.7)	93 (76.2)
Body mass index (kg/m2)	22.6	22.9	23.3 (76.2)	0.245
Previous sedation endoscopy				0.310
Yes	137 (82.5)	135 (80.8)	92 (75.4)
No	29 (17.5)	32 (19.2)	30 (24.6)
Midazolam (mg)
First dose	4.1	4.3	4.4	0.014
Second dose	1.5	1.6	1.7	0.055
Third dose	1.0	1.6	1.5	0.269
Fourth dose	1.5	1.5	1.9	0.881
Total midazolam dose (mg)	4.4	5.0	6.4	< 0.005
No. of midazolam injections	1.2	1.4	2.2	< 0.005
Time (min)
Midazolam injection to procedure start	5.1	4.5	4.7	0.327
Total procedure time	3.5	23.7	42.4	< 0.005
Inter-procedure gap			19.5
Procedure finish to antidote injection	12.8	13.1	12.1	0.482
Satisfaction with sedation during endoscopy				0.016
Very satisfied	81 (48.5)	51 (30.5)	46 (37.7)
Satisfied	74 (44.3)	86 (51.5)	58 (47.5)
Neutral	7 (4.2)	19 (11.4)	11 (9.0)
Dissatisfied	5 (3)	11 (6.6)	7 (5.7)
Very dissatisfied	-	-	-

¹Combined group: Esophagogastroduodenoscopy and colonoscopy together. EGD: Esophagogastroduodenoscopy.