Early thrombomodulin-α administration outcome for acute disseminated intravascular coagulopathy in gastrointestinal surgery

Figure 1 Alterations in disseminated intravascular coagulopathy-associated parameters between before and after 1 wk of treatment with thrombomodulin-α. Disseminated intravascular coagulopathy (DIC) scores [Japanese Association for Acute Medicine (JAAM)], systemic inflammatory response syndrome (SIRS) scores, quick-sequential organ failure assessment (qSOFA) scores, platelet (PLT) counts, prothrombin time (PT) ratios, and fibrin degradation products (FDP) values were compared for before and after 1 wk of thrombomodulin-α (TM-α) treatment. All parameters, except for FDP values, were significantly improved by TM-α administration after 1 wk. The Mann-Whitney U-test was used for the analysis.