Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis

Table 1 Comparison of untreated and treated patients with autoimmune hepatitis

Characteristic	Untreated group (n = 17)		Treated group (n = 19)		P value
	mean ± SD	95%CI	mean ± SD	95%CI
Age (yr)	62.9 ± 18.6	53.4-72.5	41.4 ± 16.8	33.30-49.5	0.001
BMI (kg/m2)	27.2 ± 6.3	24.0-30.5	28.2 ± 6.8	24.9-31.5	0.65
Serum albumin	3.81 ± 0.8	3.39-4.23	4.0 ± 0.43	3.78-4.2	0.4
Serum ALP	117.6 ± 74.7	76.3-159.0	109.4 ± 45.6	85.9-132.9	0.19
Serum ALT	298.8 ± 459.9	62.3-535.3	144.5 ± 217.8	39.5-249.4	0.22
Serum AST	238.2 ± 313.1	77.2-399.1	110.0 ± 144.4	42.6-178.0	0.12
AST/ALT	1.0 ± 0.4	0.8-1.27	0.9 ± 0.41	0.8-1.0	0.38
APRI	2.9 ± 3.47	1.1-4.67	3.2 ± 5.8	0.36-6.0	0.85
FIB-4	5.99 ± 4.94	3.4-8.53	2.7 ± 3.3	1.1-4.3	0.025
Platelet	178.9 ± 78.0	138.8-219	193.3 ± 99.0	145.6-241.0	0.63
INR	1.1 ± 0.2	1.0-1.24	1.14 ± 0.3	1.0-1.3	0.96
Total bilirubin	1.5 ± 2.3	0.3-2.69	1.5 ± 1.9	0.5-2.5	0.96
Gamma globulin	2.3 ± 0.9	1.9-2.9	2.2 ± 0.9	1.6-2.8	0.61
Mean LS (kPa)	4.1 ± 1.6	3.2-4.9	4.5 ± 2.0	3.5-5.4	0.51

ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; APRI: AST to platelet ratio index; BMI: Body mass index; FIB-4: Fibrosis 4 test; INR: International normalization ratio; LS: Liver stiffness.