Copyright
©The Author(s) 2017.
World J Gastroenterol. Dec 28, 2017; 23(48): 8660-8665
Published online Dec 28, 2017. doi: 10.3748/wjg.v23.i48.8660
Published online Dec 28, 2017. doi: 10.3748/wjg.v23.i48.8660
Type of CTLA-4-Ig fusion protein | Delay between | Endoscopic findings | Histological findings | CTLA-4-Ig | Colitis treatment | Evolution of the colitis | |
CTLA-4-Ig introduction and colitis (mo) | withdrawal | ||||||
Amezcua-Guerra et al[7] Gut 2005 | Abatacept | 15 | UC-like colitis | Lymphoplasmocytic infiltration/cryptitis/Intraluminal abscesses | Yes | Mesalazine | Clinical remission |
Motohashi et al[8] Case 1 Scand J Gastroenterol 2014 | Abatacept | 25 | UC-like colitis | Neutrophil infiltration/crypt abscesses | Yes | Infliximab + Mesalazine | NA |
Motohashi et al[8] Case 2 Scand J Gastroenterol 2014 | Abatacept | 5 | UC-like colitis | Neutrophil infiltration/crypt abscesses | Yes | Mesalazine + Prednisolone + Granulocytapheresis | NA |
Present case | Belatacept | 23 | CD-like colitis | Ulcerations/crypt abscesses/ | Yes | Prednisolone | Clinical and endoscopic remission |
lymphocytes and neutrophil infiltration |
- Citation: Bozon A, Jeantet G, Rivière B, Funakoshi N, Dufour G, Combes R, Valats JC, Delmas S, Serre JE, Bismuth M, Ramos J, Le Quintrec M, Blanc P, Pineton de Chambrun G. Stricturing Crohn’s disease-like colitis in a patient treated with belatacept. World J Gastroenterol 2017; 23(48): 8660-8665
- URL: https://www.wjgnet.com/1007-9327/full/v23/i48/8660.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i48.8660