Prognostic value of lymph node metastasis in patients with T1-stage colorectal cancer from multiple centers in China

Table 2 Multivariate analysis of correlation between lymph node metastasis and clinicopathological parameters of T1-stage colorectal cancer patients

Clinicopathological characteristic	HR	P value	95%CI
			Lower bound	Upper bound
Gender, Male vs Female	1.636	0.201	0.698	5.518
Age (yr), < 60 vs ≥ 60	0.063	0.801	0.357	2.218
Smoking No vs Yes	0.880	0.348	0.529	6.077
Preoperative CEA (ng/mL) < 5 vs ≥ 5	1.188	0.276	0.603	5.904
Preoperative CA199 (ng/mL) < 9 vs ≥ 9	2.765	0.096	0.869	5.541
Preoperative CA724 (ng/mL) < 2 vs ≥ 2	5.461	0.019	1.232	10.783
Granulocyte absolute value, < 2.2 vs ≥ 2.2	0.004	0.951	0.285	3.797
D-dimer < 0.21 vs ≥ 0.21	1.398	0.237	0.651	5.652
Preoperative hemoglobin < 132 vs ≥ 132	0.437	0.508	0.249	1.992
Tumor size (cm), < 3 vs ≥ 3	2.090	0.148	0.185	1.290
Vascular invasion, No vs Yes	8.461	0.004	2.358	81.596
Tumor location, Rectum vs Colon	0.264	0.607	0.485	3.444
Differentiation degree, High/moderate vs Low	4.204	0.040	1.057	11.956
Tumor general type, Non-ulcer vs Ulcer	0.686	0.407	0.556	4.239
Tissue type, Non-adenocarcinoma vs Adenocarcinoma	0.897	0.344	0.043	2.989