Childhood-onset inflammatory bowel diseases associated with mutation of Wiskott-Aldrich syndrome protein gene

Table 3 Clinical features of three patients with WAS c.1378C>T, p.Pro460Ser mutation

Patient	Sex	Diagnosis	Age at onset	Clinical symptoms	Platelet count (× 103/μL) /mean platelet volume (fl)	Present status and treatment
Patient 1	M	CD	12 yr	Fever, Eczema, Watery diarrhea	431/8.9	Remission mesalazine, azathioprine and infliximab
Patient 2	M	UC	11 yr	Mucous-bloody diarrhea	220/10.4	Remission mesalazine and azathioprine
Patient 3	M	UC	2 yr	Mucous-bloody diarrhea	339/9.4	Remission mesalazine and prednisolone enema

UC: Ulcerative colitis; CD: Crohn’s disease; mean platelet volume (fl), normal 8.9-12.6.