Childhood-onset inflammatory bowel diseases associated with mutation of Wiskott-Aldrich syndrome protein gene

Table 2 Previous reports of the c.1378C>T, p.Pro460Ser mutation of WAS

Phenotype	Sex	Age at onset	Platelet (×103/μL)	WASP expression	Ref.
XLT	M	8 mo	65-100	low	Lutskiy et al[20]
XLT	M	4 d	low	low	Lee et al[21]
WAS	M	N.D.	low	N.D.	Gulácsy et al[22]1
XLT	M	6 yr	5	low	Ouchi-Uchiyama et al[23]

¹This patent has double mutation (p.Pro460Ser and p.Met474Thr). ND: No data; XLT: X-linked thrombocytopenia; WAS: Wiskott-Aldrich syndrome; WASP: Wiskott-Aldrich syndrome protein.