Fructo-oligosaccharide intensifies visceral hypersensitivity and intestinal inflammation in a stress-induced irritable bowel syndrome mouse model

Figure 3 Effect of oral gavage of fructo-oligosaccharide on intestinal histological scores. A: Ileal tissues stained with hematoxylin-eosin (HE) for evaluation of inflammation score (magnification, 200×); B: No difference in structural histology among the four groups; C: Colonic tissues stained with H&E for evaluation of inflammation score (magnification, 200×); D: No difference in structural histology among the four groups. Values represent median with 5^th and 95^th percentiles; sham + saline (n = 7), sham + FOS (n = 7), WAS + saline (n = 6), WAS + FOS (n = 7); Kruskal-Wallis one-way ANOVA. FOS: Fructo-oligosaccharide; WAS: Water avoidance stress.