Effects of initiating time and dosage of Panax notoginseng on mucosal microvascular injury in experimental colitis

Figure 4 Panax notoginseng repaired colonic mucosal injuries and microvessels. IA- and DSS-induced experimental colitis groups were treated with PN (0.5, 1.0 and 2.0 g/kg) for seven consecutive days. A, C: Colonic mucosal injuries and microvessels significantly improved; B, D, E: Microvessel density increased compared with the control groups in a dose-dependent manner. Results are expressed as mean ± SD of three independent experiments performed in triplicate. ^bP < 0.01 vs normal control. DSS: Dextran sodium sulfate; IA: Iodoacetamide; PN: Panax notoginseng.