Effects of initiating time and dosage of Panax notoginseng on mucosal microvascular injury in experimental colitis

Figure 3 Panax notoginseng blocked oxidative stress in colonic mucosa. Activities of MPO and SOD in colonic tissue were used to evaluate the anti-oxidative effect of PN. A-D: The increased activity of MPO and decreased activity of SOD in the experimental colitis groups were reversed by PN in a time- and dose-dependent manner. Results are expressed as mean ± SD of three independent experiments performed in triplicate. ^aP < 0.05, ^bP < 0.01 vs normal control. MPO: Myeloperoxidase; PN: Panax notoginseng; SOD: Superoxide dismutase.