Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease

doi:10.3748/wjg.v23.i47.8300

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Dec 21, 2017 (publication date) through Feb 24, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 21, 2017; 23(47): 8300-8307
Published online Dec 21, 2017. doi: 10.3748/wjg.v23.i47.8300

Table 6 Allele and genotype frequencies of NOS2A TAAA polymorphism in inflammatory bowel disease patients and controls n (%)

	Controls	IBD patients	CD patients	UC patients
	n = 295	n = 190	n = 132	n = 58
Genotype
220/220	189 (64.07)	132 (69.47)	90 (68.18)	42 (72.41)
220/224	97 (32.88)	49 (25.79)	34 (25.76)	15 (25.86)
224/224	9 (3.05)	9 (4.74)	8 (6.06)	1 (1.72)
Allele	2n = 590	2n = 380	2n = 264	2n = 116
220	475 (80.5)	313 (82.4)	214 (81)	99 (85.3)
224	115 (19.5)	67 (17.6)	50 (19)	17 (14.7)

No statistically significant differences were found in any of the comparisons. IBD: Inflammatory bowel disease; CD: Crohn’s disease; UC: Ulcerative colitis.

Citation: Senhaji N, Nadifi S, Zaid Y, Serrano A, Rodriguez DAL, Serbati N, Karkouri M, Badre W, Martín J. Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease. World J Gastroenterol 2017; 23(47): 8300-8307
URL: https://www.wjgnet.com/1007-9327/full/v23/i47/8300.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i47.8300