Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease

Table 4 Allelic frequencies of (CCTTT)n microsatellite polymorphism of NOS2A gene for Moroccan inflammatory bowel disease patients and healthy controls n (%)

Repeat No.	Size (bp)	Controls	IBD	P value	OR (95%CI)
		2n = 596	2n = 382
7	171	2 (0.3)	4 (1.04)	0.16	3.14 (0.57-17.24)
8	176	37 (6.2)	39 (10.2)	0.021	1.71 (1.07-2.74)
9	181	75 (12.5)	54 (14.1)	0.48	1.14 (0.78-1.66)
10	186	89 (15.0)	46 (12.04)	0.20	0.77 (0.53-1.14)
11	191	90 (15.1)	45 (11.8)	0.14	0.75 (0.51-1.10)
12	196	131 (22.0)	81 (21.2)	0.77	0.95 (0.69-1.30)
13	201	99 (16.6)	50 (13.9)	0.13	0.75 (0.52-1.09)
14	206	36 (6.2)	38 (9.9)	0.022	1.71 (1.06-2.76)
15	211	33 (5.5)	22 (5.8)	0.88	1.04 (0.59-1.81)
16	216	4 (0.6)	3 (0.7)	0.83	1.17 (0.26-5.26)

¹P = 0.02, OR (95%CI): 1.71 (1.07-2.74): Bonferroni’s corrected P_c = 0.2;

²P = 0.02, OR (95%CI): 1.71 (1.06-2.76): P_c = 0.2. IBD: Inflammatory bowel disease.