Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease

Table 2 Minor Allele Frequencies of HIF1A and NFKB1 genetic variants in inflammatory bowel disease patients and healthy controls from Morocco

Gene	SNP	Group	Number of alleles	MAF (%)	Allele test
					OR (95%CI)	P value
HIF1A	rs11549467	Controls (n = 308)	74/542	12.01
		IBD (n = 199)	50/348	12.56	1.05 (0.72-1.54)	0.79
		CD (n = 136)	36/236	13.24	1.12 (0.73-1.71)	0.61
		UC (n = 63)	14/112	11.11	0.92 (0.50-1.68)	0.77
NFKB1	rs28362491	Controls (n = 308)	257/359	41.72
	-94ATTG ins/del	IBD (n = 199)	167/231	41.96	1.01 (0.78-1.30)	0.93
		CD (n = 136)	113/159	41.54	0.99 (0.74-1.33)	0.96
		UC (n = 63)	54/72	42.86	1.05 (0.71-1.54)	0.81

IBD: Inflammatory bowel disease; CD: Crohn’s disease; UC: Ulcerative colitis; MAF: Minor allele frequencies.