Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing

Table 1 Summary of stool samples collected and analyzed

Tumor location	Total collected samples	Successful DNA extraction	Successful sequencing	Number of cases with only known mutations	Number of cases with
					Mutations, all
Stomach	41	35	32 (78)	5 (15.6)	8 (25)
Carcinoma	38	32	29	3	6
Intestinal type	18	17	15	1	1
Diffuse type	20	15	14	2	5
Benign	3	3	3	2	2
Hamartoma	1	1	1	0	0
Dysplasia	1	1	1	1	1
NET	1	1	1	1	1
Colorectal	46	42	40 (87)	12 (30)	12 (30)
Carcinoma	40	37	35	9	9
Benign	6	5	5	3	3
Adenoma	4	3	3	2	2
Dysplasia	1	1	1	0	0
Leiomyoma	1	1	1	1	1
Healthy controls	14	13	13 (92.9)	0	2 (15)
Total	101	90	85	17	22

Data are presented as n or n (%). NET: Neuroendocrine tumor.