Obese children with fatty liver: Between reality and disease mongering

Table 1 Studies with histologically documented cases of advanced liver disease in pediatric nonalcoholic fatty liver disease

Study	Yr	No. of patients	Age (yr)	Follow-up (yr)	Case of cirrhosis	Progression of fibrosis (n)	Case of liver transplantation (n)
					(n)
Cross-sectional studies
Kinugasa et al[17]	1984	299	N/A	N/A	1	N/A	N/A
Schwimmer et al[16]	2003	43	N/A	N/A	1	N/A	N/A
Suzuki et al[15]	2005	1	12	N/A	1	N/A	N/A
Schwimmer et al[18]	2005	100	Range 2-18	N/A	3	N/A	N/A
Alkhouri et al[19]	2012	203	Mean 12.4	N/A	0	N/A	N/A
Longitudinal studies
Molleston et al[14]	2002	2	10 and 14	N/A	2	2/2	None
Feldstein et al[4]	2009	66	Mean 13.9	6.4	2	4/5	2
		(5 followed longitudinally)
A-Kader et al[21]	2008	106	Range 7-19	2.3	2	7/18	N/A
		(18 followed longitudinally)
Lavine et al[22]	2012 (preliminary report)	58	Range 8-17	1.8	N/A	15/58	N/A
Brunt et al[23]	2014 (preliminary report)	102	Range 11-17	2.2	N/A	20/102	N/A
Alkhouri et al[24]	2015 (preliminary report)	330	4-40	N/A	N/A	N/A	14/330

N/A: Not available.