Efficacy of noninvasive evaluations in monitoring inflammatory bowel disease activity: A prospective study in China

Table 2 Descriptive statistics of noninvasive evaluations for endoscopy-based classification of inflammation for inflammatory bowel disease and irritable bowel syndrome patients

	CICD		CD-related surgery		UC		IBS
	Inactive, n = 21	Active, n = 35	Inactive, n = 15	Active, n = 10	Inactive, n = 12	Active, n = 33	n = 25
FC (µg/g)
Median	131.7213	1795.812	142.973	229.272	45.3113	690.612	9.923
Range	(0-658.71)	(264.64-2266.07)	(0.02-1805.0)	(0-1805.0)	(6.7-189.42)	(74.93-2266.01)	(0-385.4)
CDAI/CAI							NA
Median	63.121	168.451	81	135.64	11	61
Range	(32.2-155.0)	(46.8-364.0)	(37.8-192.8)	(38. 8-327.1)	(0-4)	(1-17)
CRP (mg/L)							NA
Median	0.481	20.571	2.1	4.37	0.391	41
Range	(0.10-12.88)	(0.2-79.8)	(0.13-134.6)	(0.10-41.20)	(0.04-2.1)	(0.08-65.40)
ESR (mm/h)							NA
Median	8.01	30.01	9	17	4.31	141
Range	(1.0-57.0)	(5.0-123.0)	(1.0-92.0)	(2.0-41.0)	(2.0-15.0)	(2.0-100.0)
PCT (ng/mL)							NA
Median	0.037	0.043	0.028	0.025	0.028	0.025
Range	(0-4.39)	(0-5.02)	(0-0.082)	(0-0.058)	(0-0.082)	(0-0.058)

¹Identical letters indicate significant differences between the three inactive and active IBD patient groups (Mann-Whitney U-tests, P < 0.001 for all);

²For all indices, IBS patients had significantly lower FC levels than the three groups of active IBD patients (Mann-Whitney U-tests, P < 0.001 for all);

³IBS patients had significantly lower FC levels than the three groups of endoscopic remission IBD patients (Mann-Whitney U-tests, for CICD and CD-related surgery patients, P < 0.001; for UC patients, P < 0.05). CICD: Colonic or ileo-colonic Crohn’s disease; CD: Crohn’s disease; UC: Ulcerative colitis; IBD: Inflammatory bowel disease; IBS: Irritable bowel syndrome; FC: Fecal calprotectin; CDAI/CAI: Clinical activity index; PCT: Procalcitonin; NA: Not applicable.