Characteristics of fecal microbial communities in patients with non-anastomotic biliary strictures after liver transplantation

Table 1 Characteristics of subjects n (%)

	Healthy,(n = 10)	Post-LT
		Uncomplicated, (n = 10)	NAS,(n = 10)
Age (yr)	38 ± 12	43 ± 11	42 ± 9
Male	9 (90.0)	8 (80.0)	8 (80.0)
BMI (kg/m2)	23.3 ± 2.5	22.1 ± 2.6	22.4 ± 2.7
Current smoking	3 (30.0)	2 (10.0)	0
Current drinking	2 (20.0)	0	0
Blood routine test
HB (g/L)	122.5 ± 12.7	129.0 ± 20.0	127.4 ± 9.0
WBC (×109)	6.0 ± 1.7	5.1 ± 2.2	5.2 ± 2.5
Neu (%)	59.6 ± 14.8	66.4 ± 16.4	64.3 ± 20.0
Liver function
AST (U/L)	21.3 (7.9-39.6)	41.0 (13.0-93.0)	57.1 (17.0-107.0)ac
ALT (U/L)	20.1 (14.6-34.4)	49.3 (12.0-89.1)	57.3 (18.0-111.0)ac
ALP (U/L)	77.3 ± 31.7	93.9 ± 17.2	332.8 ± 52.4ac
GGT (U/L)	27.2 ± 8.2	53.3 ± 35.6	226.4 ± 83.4ac
TB (μmol/L)	13.7 ± 6.7	27.4 ± 17.6	104.43 ± 47.8ac
DB (μmol/L)	5.4 ± 3.1	12.5 ± 8.6	43.8 ± 6.8ac
ALB (g/L)	41.1 ± 2.9	41.9 ± 5.3	34.1 ± 5.0ac

Healthy: Healthy non-LT individuals, n = 10; NAS: Patients diagnosed with non-anastomotic biliary strictures after liver transplantation, n = 10; Uncomplicated: Patients with no complications after liver transplantation, n = 10. Blood routine tests and liver function indexes were obtained within 48 h before sample collecting. Data are presented as mean ± standard deviation, median (range), or percentage where appropriate.

^aP < 0.05 vs healthy control group;

^cP < 0.05 vs uncomplicated group. BMI: Body mass index; HGB: Hemoglobin, WBC: White blood cells; Neu%: Neutrophil ratio; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALP: Alkaline phosphatase; GGT: Gamma-glutamyltransferase; ALB: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin; LT: Liver transplantation.