Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease

Table 6 Univariate and multivariate regression analyses of full and partial work disability in patients with ulcerative colitis n (%)

	Full disability	Partial disability	Unadj. OR (95%CI)	Adj. OR (95%CI)
n	124 (100)	54 (100)
Sex (female)	75 (60)	26 (48)	1.65 (0.87-3.14)	-
Age
< 40 yr	25 (20)	15 (28)	1.00	1.00
40-55 yr	52 (42)	32 (59)	0.98 (0.45-2.12)	0.90 (0.40-2.03)
> 55 yr	47 (38)	7 (13)	4.03 (1.45-11.17)	3.49 (1.23-9.92)
Age at diagnosis
A1: diagnosis ≤ 16 yr	7 (6)	5 (9)	1.00	-
A2: diagnosis 17-40 yr	70 (56)	34 (63)	1.47 (0.43-4.97)
A3: diagnosis > 40 yr	47 (38)	15 (28)	2.24 (0.62-8.10)
Disease duration
≤ 15 yr	65 (52)	36 (67)	1.00	1.00
> 15 yr	59 (48)	18 (33)	1.82 (0.93-3.54)	1.78 (0.87-3.62)
Education	122 (100)	50 (100)
Low	84 (69)	37 (74)	0.78 (0.37-1.63)	-
Smoking	121 (100)	52 (100)
Yes	18 (15)	7 (13)	1.12 (0.44-2.88)	-
Disease location
E1: proctitis1	9 (8)	4 (8)	1.00	-
E2: left-sided colitis1	39 (33)	9 (18)	1.93 (0.48-7.68)	-
E3: extensive colitis1	70 (59)	38 (74)	0.82 (0.24-2.84)	-
Pouch2	24 (19)	9 (17)	1.20 (0.52-2.79)	-
Stoma2	23 (19)	8 (15)	1.31 (0.54-3.15)	-
Surgery2	37 (30)	14 (26)	1.22 (0.59-2.50)	-
Medication	122 (100)	53 (100)
Anti-TNFα	30 (25)	10 (19)	1.40 (0.63-3.13)	-
Immunomodulators	77 (63)	37 (70)	0.74 (0.37-1.48)	-
Extra-intestinal manifestations2	51 (41)	19 (35)	1.29 (0.66-2.50)	-
PSC2	3 (2)	4 (7)	0.31 (0.07-1.44)	-
Complications2	28 (23)	4 (7)	3.65 (1.21-10.97)	3.39 (1.09-10.58)

¹These percentages are calculated for 118 patients with UC that were fully disabled and 51 patients with UC that were partially disabled;

²Missing values were scored as non-present. UC: Ulcerative colitis; Unadj: Unadjusted; Adj: Adjusted; TNFα: Tumor necrosis factor alpha; PSC: Primary sclerosing cholangitis.