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Copyright ©The Author(s) 2017.
World J Gastroenterol. Dec 14, 2017; 23(46): 8120-8127
Published online Dec 14, 2017. doi: 10.3748/wjg.v23.i46.8120
Table 1 Representative direct-acting antivirals, their targets and hepatitis C virus genotypes
Target regionsDAAsHCV GTs
NS3/4AGlecaprevirPan-GTs
Grazoprevir1, 4
Asunaprevir1b
Paritaprevir1, 2a, 4
Simeprevir1, 4
Telaprevir1, 2
Boceprevir1
NS5APibrentasvirPan-GTs
VelpatasvirPan-GTs
ElbasvirPan-GTs
DaclatasvirPan-GTs
Ledipasvir1, 4, 5
Ombitasvir1, 4
NS5BSofosbuvir [nucleos(t)ide inhibitor]Pan-GTs
Dasabuvir [non-nucleos(t)ide inhibitor]1