Circulating miR-125a but not miR-125b is decreased in active disease status and negatively correlates with disease severity as well as inflammatory cytokines in patients with Crohn’s disease

Figure 7 miR-125a/b expression in active Crohn's disease patients after treatment. After 3-mo treatment, miR-125a expression was increased in A-CD patients who achieved clinical remission but remained stable in patients who failed to achieve remission. Conversely, no changes in miR-125b expression were observed in either remission or non-remission patients after 3-mo treatment. Comparison between visits in the same group was performed by the Wilcoxon signed-rank test. P < 0.05 was considered significant. A-CD: Active Crohn's disease.