Circulating miR-125a but not miR-125b is decreased in active disease status and negatively correlates with disease severity as well as inflammatory cytokines in patients with Crohn’s disease

Figure 1 miR-125a/b expression in active Crohn's disease patients, patients with Crohn's disease in remission, and healthy controls. miR-125a was decreased in A-CD patients compared with R-CD patients and HCs (A), while no differences in miR-125b were detected between groups. Comparison between two groups was performed by the Wilcoxon signed-rank test. P < 0.05 was considered significant. A-CD: Active Crohn's disease; R-CD: Crohn's disease in remission; HCs: Healthy controls.