Prediction of early-stage hepatocellular carcinoma using OncoScan chromosomal copy number aberration data

doi:10.3748/wjg.v23.i44.7818

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Nov 28, 2017 (publication date) through Jul 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2017; 23(44): 7818-7829
Published online Nov 28, 2017. doi: 10.3748/wjg.v23.i44.7818

Table 3 Cox regression analysis for disease-free survival in early-stage hepatocellular carcinoma

Gene	Cytoband	CNA	HR	95%CI	P value
ELAC2	17p12	Amplification	2.784	1.153-6.724	0.023^a
MYC	8q24.21	Amplification	1.772	1.074-2.924	0.025^a
SYK	9q22.2	Amplification	4.204	1.813-9.748	0.001^a
GAK	4p16.3	Deletion	2.916	1.635-5.199	< 0.001^a
MECOM	3q26.2	Deletion	5.932	2.012-17.489	0.001^a
WRN	8p12	Deletion	1.9	1.172-3.080	0.009^a

^aP < 0.05, statistically significant. HCC: Hepatocellular carcinoma; CNA: Copy number aberration; HR: Hazard ratio; CI: Confidence interval.

Citation: Yu MC, Lee CW, Lee YS, Lian JH, Tsai CL, Liu YP, Wu CH, Tsai CN. Prediction of early-stage hepatocellular carcinoma using OncoScan chromosomal copy number aberration data. World J Gastroenterol 2017; 23(44): 7818-7829
URL: https://www.wjgnet.com/1007-9327/full/v23/i44/7818.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i44.7818