Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats

Figure 2 Influence of resveratrol administration and bile duct obstruction on the bile flow rate (A), biliary excretion of azithromycin (B), biliary excretion of bile acids (C), and biliary excretion of glutathione (D). Rats received either saline or resveratrol (R, 10 mg/kg) daily by oral gavage for 28 d after surgical procedure. Data are presented as the mean ± SE (n = 6). ^aP < 0.05, ^bP < 0.01, ^eP < 0.001 vs saline-treated sham group; ^cP < 0.05 vs saline-treated BDO group. BE: Biliary excretion; BDO: Bile duct obstruction.