Copyright
©The Author(s) 2017.
World J Gastroenterol. Nov 21, 2017; 23(43): 7657-7665
Published online Nov 21, 2017. doi: 10.3748/wjg.v23.i43.7657
Published online Nov 21, 2017. doi: 10.3748/wjg.v23.i43.7657
Figure 2 Mechanisms for the pathogenesis of hepatitis B virus-induced liver diseases via mitochondrial damage and endoplasmic reticulum stress.
Plus and minus symbols are up- and down-regulated responses, respectively. HBV: Hepatitis B virus; cccDNA: Covalently closed circular DNA; ER: Endoplasmic reticulum; HBx: Hepatitis B virus X protein; ROS: Reactive oxygen species; ATF4: Activating transcription factor 4; XBP1: X-box binding protein 1; ATF6: Activating transcription factor 6.
- Citation: Kim SY, Kyaw YY, Cheong J. Functional interaction of endoplasmic reticulum stress and hepatitis B virus in the pathogenesis of liver diseases. World J Gastroenterol 2017; 23(43): 7657-7665
- URL: https://www.wjgnet.com/1007-9327/full/v23/i43/7657.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i43.7657