Laparoscopic VS open hepatectomy for hepatolithiasis: An updated systematic review and meta-analysis

Table 4 Sensitivity analysis in laparoscopic hepatectomy vs open hepatectomy

Outcomes of interest	Study, n	LH, n	OH, n	WMD/OR (95%CI)	P	Study heterogeneity			P
						χ2	df	I2, %
Operative time, min	11	416	464	26.58 (-1.78, 54.94)	0.07	201.48	10	95	< 0.001
Estimated blood loss, mL	9	402	445	-56.21 (-108.00, -4.43)	0.03	73.92	9	88	< 0.001
Intraoperative transfusion	7	314	366	0.47 (0.23, 0.97)	0.04	8.03	6	25	0.24
Length of hospital stay, d	12	450	504	-3.47 (-4.67, -2.27)	< 0.001	47.8	11	77	< 0.001
Postoperative complications	12	451	504	0.55 (0.38, 0.78)	< 0.001	8.33	11	0	0.68
Time to oral intake, d	6	187	267	-1.12 (-1.56, -0.68)	< 0.001	70.78	5	93	< 0.001
Initial residual stone	10	381	445	0.90 (0.53, 1.53)	0.71	2.74	9	0	0.97
Final residual stone	5	136	146	0.34 (0.11, 1.08)	0,07	2.92	4	0	0.57
Stone recurrence	10	394	445	0.59 (0.31, 1.15)	0.12	3.01	9	0	0.96

df: Degrees of freedom; LH: Laparoscopic hepatectomy; OH: Open hepatectomy; WMD/OR: Weight mean difference/odds ratio.