Potential rat model of anxiety-like gastric hypersensitivity induced by sequential stress

Figure 2 OF test showed the sequential-stress-treated rats demonstrated anxiety-like behavior. A: They spent less time in central area; B: They climbed fewer number of virtual grids in OF box; C: Their total exploring distance was shorter; D: Their mean moving speed was slower. Data were expressed as the mean ± SEM of the time spent in central area, number of virtual grids climbed, total exploring distance and mean moving speed (n = 8 in each group). ^aP < 0.05, ^bP < 0.01 vs control group.