Copyright
©The Author(s) 2017.
World J Gastroenterol. Nov 14, 2017; 23(42): 7519-7530
Published online Nov 14, 2017. doi: 10.3748/wjg.v23.i42.7519
Published online Nov 14, 2017. doi: 10.3748/wjg.v23.i42.7519
Figure 5 mRNA expression of nuclear receptors in rat livers.
Pregnane x receptor (A) and constitutive androstane receptor (B) gene expression in sham-operated and cholestatic rats reported as fold variations compared with sham rats. Results are mean ± SEM obtained from 8 rats in each group. aP < 0.05, cP < 0.001 vs sham rats; dP < 0.05, fP < 0.01 vs mildly cholestatic rats.
- Citation: Gabbia D, Pozza AD, Albertoni L, Lazzari R, Zigiotto G, Carrara M, Baldo V, Baldovin T, Floreani A, Martin SD. Pregnane X receptor and constitutive androstane receptor modulate differently CYP3A-mediated metabolism in early- and late-stage cholestasis. World J Gastroenterol 2017; 23(42): 7519-7530
- URL: https://www.wjgnet.com/1007-9327/full/v23/i42/7519.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i42.7519