Region-dependent effects of diabetes and insulin-replacement on neuronal nitric oxide synthase- and heme oxygenase-immunoreactive submucous neurons

Figure 4 Proportion of HO1-immunoreactive neurons related to the total number of submucous neurons in the duodenum, ileum and colon. A: Only in controls; B: In control, diabetic and insulin-treated diabetic rats. Data are expressed as mean ± SE; ^fP < 0.0001 vs control duodenum; ^gP < 0.0001 vs control ileum, ^aP < 0.05 and ^eP < 0.0001 vs controls, and ^dP < 0.01 vs diabetics. IR: Immunoreactive; C: Controls; D: Diabetics; ID: Insulin-treated diabetics.