Endoscopic balloon dilation of Crohn’s disease strictures-safety, efficacy and clinical impact

Table 2 Univariate and multivariate analysis of risk factors for need for dilation after surgery

Risk factors	Univariate analysis	Multivariate analysis
	OR	95%CI	P value	OR	95%CI	P value
Significant in univariate and multivariate analysis
Time between surgery and index colonoscopy	1.006	1.003-1.010	0.001	1.007	1.001-1.013	0.027
Lactoferrin levels	1.010	1.000-1.021	0.049	1.012	1.000-1.024	0.043
Significant in univariate analysis
Subocclusive symptoms	6.155	2.546-14.880	< 0.001	-	-	0.180
No medical treatment with thiopurines	2.611	1.282-5.319	0.008	-	-	0.500
Age at index colonoscopy	1.028	1.002-1.055	0.033	-	-	0.932
Not significant in univariate nor multivariate analysis
Smoking status	1.877	0.912-3.861	0.087
B2 behavior	1.221	0.619-2.408	0.565
B3 behavior	0.895	0.454-1.767	0.750
Perianal disease	1.376	0.632-2.996	0.421
Anti-TNF therapy	0.893	0.443-1.799	0.751
C-reactive protein levels	0.975	0.935-1.016	0.229
Calprotectin levels	1.001	1.000-1.002	0.125
Harvey-Bradshaw index	1.111	0.936-1.318	0.229
Disease duration	1.002	1.000-1.005	0.089

OR: Odds ratio; CI: Confidence interval; B1: Non-stenosing and non-penetrating behaviour; B2: Stenosing behaviour; B1: Penetrating behaviour; TNF: Tumor necrosis factor.