Hypothermic machine perfusion with metformin-University of Wisconsin solution for ex vivo preservation of standard and marginal liver grafts in a rat model

Figure 4 Staining of the slices of ex vivo rat liver tissue. A and D: The young control group A and the aged control group D, respectively; B and E: The young group B and aged group E of UWP, respectively; C and F: The young group C and the aged group F of MUWP, respectively; G: Histopathologic scoring of structural injury in each group. Data are presented as mean ± SD (n = 6) and compared by Kruskal-Wallis one-way analysis of variance on ranks and Mann-Whitney U test. ^aP < 0.05 vs group B of UWP; ^bP < 0.05 vs group E of UWP. Original magnification (A-F): × 400. UWP: University of Wisconsin solution perfusion; MUWP: Metformin perfusion solution.