Hypothermic machine perfusion with metformin-University of Wisconsin solution for ex vivo preservation of standard and marginal liver grafts in a rat model

Figure 2 Analysis of inflammatory factors in the perfused liquid. The IL-18 and TNF-α levels in the perfused liquid (mean ± SD) of the ex vivo livers of the three groups: CTRL (control groups A and D), UWP (UW solution perfusion groups B and E), and MUWP (metformin perfusion groups C and F). Data are presented as mean ± SD (n = 6) and compared by two-way analysis of variance and the Tukey's and Sidak's multiple comparisons tests. ^aP < 0.05 vs group B; ^bP < 0.05 vs group E; ^cP < 0.05 vs group B; ^dP < 0.05 vs group E.