Observational Study
Copyright ©The Author(s) 2017.
World J Gastroenterol. Oct 28, 2017; 23(40): 7321-7331
Published online Oct 28, 2017. doi: 10.3748/wjg.v23.i40.7321
Table 4 Health-related quality of life in patients with high, medium and low medication adherence
Quality of life domainsAll patients(n = 100)Medication adherence ranking
P value
HighMediumLow
(n = 42)(n = 37)(n = 21)
Abdominal symptoms4.7 ± 1.54.6 ± 1.45.1 ± 1.44.2 ± 1.60.063
Abdominal bloating4.5 ± 2.04.3 ± 2.04.9 ± 1.83.9 ± 2.10.109
Abdominal pain4.9 ± 1.84.8 ± 1.75.5 ± 1.54.1 ± 2.20.023
Abdominal discomfort4.4 ±1.84.7 ± 1.84.9 ± 1.74.6 ± 1.90.715
Activity4.5 ± 1.54.6 ± 1.64.5 ± 1.34.1 ± 1.50.377
Not been able to eat as much as you would like5.1 ± 1.95.0 ± 2.05.2 ± 1.65.0 ± 2.00.814
Trouble lifting or carrying heavy objects3.4 ± 2.13.8 ± 2.33.3 ± 1.92.5 ± 1.90.067
Bothered by a limitation of your diet5.0 ± 1.95.0 ± 1.95.0 ± 2.04.7 ± 2.10.824
Emotion4.3 ± 1.54.7 ± 1.34.3 ± 1.73.7 ± 1.30.050
Anxiety4.4 ± 1.94.8 ± 1.64.3 ± 2.13.8 ± 1.80.126
Unhappiness4.5 ± 1.94.8 ± 1.94.6 ± 2.13.8 ± 1.30.125
Irritability4.7 ± 1.75.0 ± 1.64.9 ± 1.83.8 ± 1.40.017
Difficulty sleeping at night3.6 ± 2.24.0 ± 2.13.4 ± 2.33.1 ± 2.20.259
Mood swings4.7 ± 1.95.1 ± 1.74.7 ± 2.13.8 ± 1.70.031
Unable to fall asleep at night3.9 ± 2.34.1 ± 2.33.7 ± 2.33.7 ± 2.30.687
Felt depressed4.6 ± 1.95.1 ± 1.84.5 ± 2.13.9 ± 1.60.058
Problems concentrating4.3 ± 1.94.5 ± 2.04.5 ± 1.93.7 ± 1.90.232
Fatigue3.2 ± 1.53.5 ± 1.63.3 ± 1.52.9 ± 1.30.340
Tired or fatigued3.0 ± 1.63.0 ± 1.63.1 ± 1.72.7 ± 1.40.622
Sleepy during the day3.2 ± 1.83.3 ± 1.93.5 ± 2.02.7 ± 1.20.255
Bothered by having decreased strength3.6 ± 2.03.9 ± 2.03.4 ± 2.03.1 ± 2.00.281
Decreased level of energy3.0 ± 1.83.2 ± 1.72.9 ± 1.82.6 ± 1.60.361
Drowsiness3.9 ± 1.74.1 ± 1.83.8 ± 1.73.6 ± 1.60.466
Systemic symptoms4.3 ± 1.34.3 ± 1.24.4 ± 1.44.0 ± 1.50.519
Bodily pain4.2 ± 2.04.2 ± 1.84.7 ± 2.23.3 ± 2.00.037
Shortness of breath4.5 ± 1.95.0 ± 1.84.4 ± 1.93.7 ± 1.80.030
Muscle cramps4.2 ± 1.94.2 ± 2.04.1 ± 1.74.2 ± 2.20.957
Dry mouth3.9 ± 2.04.0 ± 2.03.9 ± 2.03.7 ± 1.90.833
Itching4.5 ± 2.14.2 ± 2.24.6 ± 2.05.0 ± 2.10.392
Worry3.9 ± 1.84.1 ± 1.83.8 ± 2.03.6 ± 1.60.491
Worry about impact of liver disease has on family/friends3.9 ± 2.14.0 ± 2.03.9 ± 2.23.7 ± 2.20.876
Worried that symptoms will develop into major problems3.7 ± 2.14.0 ± 2.13.6 ± 2.23.1 ± 2.00.357
Worry about condition getting worse3.9 ± 2.04.1 ± 2.03.7 ± 2.13.6 ± 2.00.569
Worry about never feeling any better4.2 ± 2.24.5 ± 2.24.2 ± 2.33.8 ± 1.80.436