Clinical features of alcoholic hepatitis in latinos and caucasians: A single center experience

Table 5 Cox proportional hazards analyses of overall survival by subject characteristics¹

	All subjects		Caucasian subjects		Latino subjects
	HR (95%CI)	P value	HR (95%CI)	P value	HR (95%CI)	P value
History of GI bleeding: yes vs no	0.79 (0.49, 1.28)	0.339	0.91 (0.53, 1.54)	0.718	0.39 (0.09, 1.72)	0.213
History of SBP: yes vs no	0.95 (0.50, 1.80)	0.874	0.86 (0.37, 2.01)	0.727	0.98 (0.37, 2.62)	0.97
ICU Admission: yes vs No	1.32 (0.80, 2.19)	0.278	1.42 (0.79, 2.56)	0.237	1.31 (0.45, 3.81)	0.618
MELD score2	1.88 (1.39, 2.55)	< 0.001	1.86 (1.29, 2.69)	0.001	2.15 (1.19, 3.87)	0.011
Child-turcotte-pugh score: C vs A or B	2.85 (1.62, 5.00)	< 0.001	2.62 (1.36, 5.07)	0.004	4.3 (1.24, 14.9)	0.021
Initial glasgow score: > 9 vs < 9	1.86 (1.18, 2.93)	0.008	1.6 (0.93, 2.74)	0.091	2.91 (1.21, 6.97)	0.017
Initial maddrey score: > 32 vs < 32	2.41 (1.29, 4.49)	0.006	1.82 (0.95, 3.50)	0.072	3	3
Treatment with steroids: yes vs no	1.63 (0.89, 2.98)	0.113	1.68 (0.81, 3.51)	0.164	2.05 (0.61, 6.88)	0.247
Duration of treatment with steroids: ≥ 28 d vs < 28 d	2.23 (0.66, 7.58)	0.198	5.28 (0.69, 40.5)	0.110	1.03 (0.01, 83.3)	0.988
Renal function: CKD 1 or higher vs CKD 0	7.43 (2.74, 20.1)	< 0.001	7.74 (2.8, 21.4)	< 0.001	3	3
Hepatorenal syndrome: yes vs no	7.07	< 0.001	7.77	< 0.001	5.65	0.006
	(3.95, 12.7)		(3.92, 15.4)		(1.66, 19.2)

¹A separate analysis was conducted for each risk factor shown. All analyses were adjusted for age, sex, BMI, and, for analyses in all subjects, ethnicity;

²Change in hazard of death for 10 point increase in actual MELD score;

³Not enough data to analyze. GI bleeding: Gastrointestinal bleeding; SBP: Spontaneous bacterial peritonitis; ICU: Intensive care unit; MELD: Model for end stage liver disease; CKD: Chronic kidney disease.