Comparative study: Vonoprazan and proton pump inhibitors in Helicobacter pylori eradication therapy

Figure 2 Helicobacter pylori eradication rates (full analysis set) for vonoprazan, esomeprazole, rabeprazole, and lansoprazole in second-line triple therapy. The eradication rates of the four second-line therapies were not significantly different. VPZ 20: 20 mg VPZ, 250 mg MNZ, and 750 mg AMPC twice a day for 1 wk; EPZ 20: 20 mg EPZ, 250 mg MNZ, and 750 mg AMPC twice a day for 1 wk; RPZ 10: 10 mg RPZ, 250 mg MNZ, and 750 mg AMPC twice a day for 1 wk; LPZ 30: 30 mg LPZ, 250 mg MNZ, and 750 mg AMPC twice a day for 1 wk. VPZ: Vonoprazan; MNZ: Metronidazole; AMPC: Amoxicillin; EPZ: Esomeprazole; RPZ: Rabeprazole; LPZ: Lansoprazole; H. pylori: Helicobacter pylori.