Mutational analysis of hepatitis E virus ORF1 "Y-domain": Effects on RNA replication and virion infectivity

doi:10.3748/wjg.v23.i4.590

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Jan 28, 2017 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2017; 23(4): 590-602
Published online Jan 28, 2017. doi: 10.3748/wjg.v23.i4.590

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Figure 5 Molecular characterization of hepatitis E virus Y-domain sequences. A: Agarose-gel electropherograms showing the gross RNA yield of pSK-GFP saturation mutants: Ydom1 to Ydom10 (left panel) and specific amino acid mutants: YdomC₃₃₆A, YdomC₃₃₇A and YdomW₄₁₃A (right panel), compared to wild-type (WT); B: Flow cytometry analysis of GFP-positive S10-3 cells, showing the replication competence of the Y-domain mutant replicons.

Citation: Parvez MK. Mutational analysis of hepatitis E virus ORF1 "Y-domain": Effects on RNA replication and virion infectivity. World J Gastroenterol 2017; 23(4): 590-602
URL: https://www.wjgnet.com/1007-9327/full/v23/i4/590.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i4.590