Association between endotoxemia and histological features of nonalcoholic fatty liver disease

doi:10.3748/wjg.v23.i4.712

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Jan 28, 2017 (publication date) through Jul 29, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jan 28, 2017; 23(4): 712-722
Published online Jan 28, 2017. doi: 10.3748/wjg.v23.i4.712

Table 3 Correlations between lipopolysaccharide-binding protein/EndoCab IgG and routine clinical data

	LBP		EndoCab IgG
	r	P value	r	P value
Age	-0.10	0.25	0.34¹	0.0001¹
BMI	0.11	0.23	-0.02	0.86
Leukocyte	0.31¹	0.0005¹	-0.07	0.44
Erythrocyte	0.11	0.23	-0.23	0.01
Hemoglobin	0.02	0.87	-0.20	0.024
Hematocrit	0.05	0.55	-0.22	0.013
MCV	-0.15	0.10	0.08	0.37
MCH	-0.15	0.92	0.10	0.25
MCHC	-0.15	0.11	0.02	0.81
Platelet	0.22	0.015	-0.29	0.001
PT-INR	-0.13	0.15	0.12	0.18
APTT	0.06	0.51	0.08	0.37
FIBG	0.30¹	0.0009¹	-0.05	0.59
Total protein	-0.01	0.91	0.12	0.18
Albumin	-0.02	0.84	-0.17	0.06
Bilirubin	-0.23	0.01	-0.03	0.73
AST	0.38¹	< 0.0001¹	0.07	0.44
ALT	0.35¹	< 0.0001¹	-0.09	0.31
LDH	0.24	0.006	0.13	0.16
ALP	0.16	0.07	0.08	0.39
γGT	0.21	0.02	-0.06	0.53
ChE	-0.04	0.69	-0.21	0.02
Urea nitrogen	-0.24	0.007	-0.08	0.35
Creatinine	-0.05	0.60	-0.26	0.004
Uric acid	0.07	0.47	-0.21	0.02
eGFR	0.15	0.12	-0.02	0.85
Total cholesterol	0.09	0.31	0.02	0.86
Triglycerides	0.07	0.46	0.11	0.22
LDL-cholesterol	0.08	0.37	0.001	0.99
HDL-cholesterol	-0.06	0.54	-0.001	0.99
Glucose	-0.08	0.35	0.19	0.04
Insulin	0.17	0.07	0.01	0.96
HbA1c	0.05	0.59	0.27	0.002
HOMA-IR	0.14	0.14	0.04	0.65
IgG	-0.09	0.33	0.30¹	0.0009¹
IgM	0.12	0.19	-0.02	0.80
IgA	-0.10	0.28	0.25	0.006
CRP	0.47¹	< 0.0001¹	0.05	0.61
Hyaluronic acid	-0.08	0.42	0.36¹	0.0002¹
Type 4 collagen 7S	-0.04	0.65	0.17	0.08
CK18 fragment	0.28	0.002	0.002	0.98

¹Items with r≥ 0.3 and P < 0.05. Correlation coefficients (r) and P values were calculated by Spearman’s test. BMI: Body mass index; MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; MCHC: Mean corpuscular hemoglobin concentration; PT-INR: International ratio of prothrombin time; APTT: Activated partial thromboplastin test; FIBG: Fibrinogen; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; LDH: Lactate dehydrogenase; eGFR: Estimated glomerular filtration rate; ALP: Alkaline phosphatase; γGT: γ-glutamyltransferase; ChE: Cholinesterase; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; HbA1c: Hemoglobin A1c; HOMA-IR: Homeostasis model assessment for insulin resistance; CRP: C-reactive protein; CK18: Cytokeratin 18.

Citation: Kitabatake H, Tanaka N, Fujimori N, Komatsu M, Okubo A, Kakegawa K, Kimura T, Sugiura A, Yamazaki T, Shibata S, Ichikawa Y, Joshita S, Umemura T, Matsumoto A, Koinuma M, Sano K, Aoyama T, Tanaka E. Association between endotoxemia and histological features of nonalcoholic fatty liver disease. World J Gastroenterol 2017; 23(4): 712-722
URL: https://www.wjgnet.com/1007-9327/full/v23/i4/712.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i4.712