Comparative study: Vonoprazan and proton pump inhibitors in Helicobacter pylori eradication therapy

Table 2 Univariate analysis of predictors for successful Helicobacter pylori first-line eradication

	VPZ group				PPI group
	Eradication rate	OR	95%CI	P value	Eradication rate	OR	95%CI	P value
Sex
Male	90.2%	1			67.0%	1
Female	86.3%	0.682	0.396-1.174	0.17	66.9%	0.995	0.737-1.343	0.97
Age (yr)
< 60	86.6%	1			74.1%	1
≥ 60	87.9%	1	0.598-1.673	1	76.7%	1.155	0.860-1.551	0.34
BMI (kg/m2)
< 25	88.4%	1			69.1%	1
≥ 25	86.5%	0.843	0.464-1.530	0.57	68.8%	0.987	0.683-1.435	0.94
Smoking
No	87.3%	1			68.1%	1
Yes	91.3%	1.412	0.583-3.420	0.44	56.6%	0.611	0.412-0.906	0.01
Alcohol
Non-drinker	88.1%	1			67.7%	1
Drinker	87.4%	0.937	0.555-1.580	0.81	67.3%	0.984	0.716-1.352	0.92
Atrophy
Closed type	87.9%	1			65.6%	1
Open type	89.1%	1.130	0.619-2.069	0.69	65.6%	0.998	0.708-1.408	0.99

VPZ: Vonoprazan; PPI: Proton pump inhibitor.