Intraepithelial lymphocytes, scores, mimickers and challenges in diagnosing gluten-sensitive enteropathy (celiac disease)

doi:10.3748/wjg.v23.i4.573

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Jan 28, 2017 (publication date) through Jan 6, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2017; 23(4): 573-589
Published online Jan 28, 2017. doi: 10.3748/wjg.v23.i4.573

Table 2 Corazza-Villanacci classification

Grade A

Nonatrophic, with normal V:C ratio and ↑ IELs (> 25 IELs/100 enterocytes)

Grade B1

"Atrophic", V:C < 3:1, but villi still detectable and ↑ IELs (> 25 IELs/100 enterocytes)

Grade B2

Atrophic and flat, villi not detectable and ↑ IELs (> 25 IELs per 100 enterocytes)

V:C: Villous to crypt ratio (normal, V:C > 3:1); GSE: Gluten-sensitive enteropathy; IEL: Intraepithelial lymphocytes.

Citation: Sergi C, Shen F, Bouma G. Intraepithelial lymphocytes, scores, mimickers and challenges in diagnosing gluten-sensitive enteropathy (celiac disease). World J Gastroenterol 2017; 23(4): 573-589
URL: https://www.wjgnet.com/1007-9327/full/v23/i4/573.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i4.573