Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features

Table 9 The significant insertion-deletions associations with relapse risks

Gene	Model	Time of follow-up	OR (95%CI)	P value
ACE	Del/Del vs Del/Ins + Ins/Ins	2 yr	0.32 (0.13-0.77)	0.0113
ACE	Del/Del vs Del/Ins + Ins/Ins	3 yr	0.37 (0.15-0.91)	0.0298
HLAG	Del/Del vs Del/Ins + Ins/Ins	2 yr	2.75 (1.07-7.08)	0.0281
HLAG	Del/Del vs Del/Ins + Ins/Ins	4 yr	2.83 (1.07-7.52)	0.0332
HLAG	Del/Del vs Del/Ins + Ins/Ins	5 yr	3.47 (1.20-9.99)	0.0194
TYMS	Ins/Ins vs Del/Ins + Del/Del	2 yr	3.35 (1.36-8.28)	0.0058
TYMS	Ins/Ins vs Del/Ins + Del/Del	3 yr	3.42 (1.41-8.28)	0.0046
UGT1A1	Del/Del vs Del/Ins + Ins/Ins	4 yr	3.23 (1.27-8.22)	0.0116
UGT1A1	Del/Del vs Del/Ins + Ins/Ins	5 yr	3.50 (1.24-9.84)	0.0145

Logistic regression adjusted for confounders. The Supplementary Table 4 shows the genotype frequency of all insertion-deletions polymorphism.