Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features

Table 3 Genetic ancestry distribution between case and control groups

Genetic ancestry (%)	Total, n = 280	Cases, n = 140	Controls, n = 140	OR (95%CI)	P value
European	65.3 ± 15.5	64.2 ± 15.6	66.4 ± 15.3		0.243
95-80	50 (17.9)	21 (15.1)	29 (20.7)	1.0 (Reference)
80-70	70 (25.1)	33 (23.7)	37 (26.4)	1.23 (0.59-2.56)	0.577
70-60	67 (24.0)	38 (27.3)	29 (20.7)	1.81 (0.86-3.80)	0.117
60-50	47 (16.8)	22 (15.8)	25 (17.9)	1.21 (0.54-2.71)	0.634
50-40	26 (9.3)	14 (10.1)	12 (8.6)	1.61 (0.62-4.18)	0.327
40-30	11 (3.9)	6 (4.3)	5 (3.6)	1.66 (0.45-6.16)	0.451
30-20	7 (2.5)	5 (3.6)	2 (1.4)	3.45 (0.61-19.54)	0.161
20-10	1 (0.4)	-	1 (0.7)	-
Amerindian	16.2 ± 10.1	16.0 ± 10.3	16.3 ± 9.9		0.645
02-10	90 (32.3)	45 (32.4)	45 (32.1)	1.0 (Reference)
10-20	113 (40.5)	60 (43.2)	53 (37.9)	1.13 (0.65-1.97)	0.661
20-30	47 (16.8)	18 (12.9)	29 (20.7)	0.62 (0.30-1.27)	0.193
30-40	21 (7.5)	11 (7.9)	10 (7.1)	1.10 (0.42-2.85)	0.844
40-50	7 (2.5)	4 (2.9)	2 (2.1)	2.00 (0.35-11.47)	0.437
50-60	1 (0.4)	1 (0.7)	-	-
African	18.6 ± 12.0	19.8 ± 12.3	17.3 ± 11.7		0.049
02-10	81 (29.0)	36 (25.9)	45 (32.1)	1.0 (Reference)
10-20	89 (31.9)	41 (29.5)	48 (34.3)	1.07 (0.58-1.95)	0.832
20-30	66 (23.7)	38 (27.3)	28 (20.0)	1.70 (0.88-3.27)	0.114
30-40	28 (10.0)	15 (10.8)	13 (9.3)	1.44 (0.61-3.42)	0.405
40-50	8 (2.9)	5 (3.6)	3 (2.1)	2.08 (0.47-9.31)	0.337
50-60	5 (1.8)	3 (2.2)	2 (1.4)	1.87 (0.30-11.83)	0.504
60-70	2 (0.7)	1 (0.7)	1 (0.7)	1.25 (0.07-20.68)	0.876

Categorized data are presented by absolute numbers of individuals (percentage) and analyzed by Chi-square test. Continuous data are presented by mean ± standard variation and analyzed by Mann-Whitney test.