Glycosylation-related gene expression in HT29-MTX-E12 cells upon infection by Helicobacter pylori

Table 2 Glycosylation-related differentially expressed genes associated with Helicobacter pylori infection of E12 cells

Gene symbol	Fold change	P value	Gene name
Top 20 upregulated
LGALS7/7B	2.31	0.0115	Lectin, galactoside-binding, soluble, 7 /7B
UGGT1	1.98	0.0059	UDP-glucose glycoprotein glucosyltransferase 1
ST3GAL5	1.90	0.0035	ST3 beta-galactoside alpha-2,3-sialyltransferase 5
PARM1	1.87	0.0026	Prostate androgen-regulated mucin-like protein 1
NAGK	1.79	0.0016	N-acetylglucosamine kinase
VSIG1	1.71	0.0240	V-set and immunoglobulin domain containing 1
EDEM2	1.69	0.0032	ER degradation enhancer, mannosidase alpha-like 2
MPDU1	1.69	0.0029	Mannose-P-dolichol utilization defect 1
DPM2	1.61	0.0015	Dolichyl-phosphate mannosyltransferase polypeptide 2, reg. s/u
LMAN2	1.60	0.0021	Lectin, mannose-binding 2
GMPPB	1.59	0.0019	GDP-mannose pyrophosphorylase B
ALG3	1.59	0.0214	Asn-linked glycosylation 3, alpha-1,3- mannosyltransferase hom.
GALK2	1.57	0.0027	Galactokinase 2
DDOST	1.53	0.0094	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase
MCAM	1.53	0.0111	Melanoma cell adhesion molecule
B3GALT6	1.53	0.0097	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
SLC35B1	1.51	0.0025	Solute carrier family 35, member B1
ST6GALNAC4	1.50	0.0024	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
GMPPA	1.49	0.0031	GDP-mannose pyrophosphorylase A
ALDOC	1.48	0.0020	Aldolase C, fructose-bisphosphate
Top 20 downregulated
REG4	2.46	0.0018	Regenerating islet-derived family, member 4
OGT	2.25	0.0037	O-linked N-acetylglucosamine (GlcNAc) transferase (OGT)
AMIGO2	2.22	0.0039	Adhesion molecule with Ig-like domain 2
GALNT12	2.09	0.0033	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
EXT1	1.99	0.0256	Exostosin 1
LY75	1.86	0.0075	Lymphocyte antigen 75 (CLEC13B)
PIGZ	1.82	0.0072	Phosphatidylinositol glycan anchor biosynthesis, class Z
UGP2	1.79	0.0320	UDP-glucose pyrophosphorylase 2
MANEA	1.79	0.0225	Mannosidase, endo-alpha
ALG13	1.78	0.0138	Asparagine-linked glycosylation 13 homolog (S. cerevisiae)
GBAP1	1.75	0.0035	Glucosidase, beta, acid pseudogene 1
SLC35A3	1.73	0.0071	Solute carrier family 35 (UDP-N-acetylglucosamine transporter), member A3
ST3GAL4	1.71	0.0032	ST3 beta-galactoside alpha-2,3-sialyltransferase 4
B4GALNT3	1.71	0.0129	Beta-1,4-N-acetyl-galactosaminyl transferase 3
HMMR	1.70	0.0039	Hyaluronan-mediated motility receptor (RHAMM)
B4GALT6	1.69	0.0134	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
MAN2A1	1.60	0.0034	Mannosidase, alpha, class 2A, member 1
LGALS2	1.58	0.0127	Lectin, galactoside-binding, soluble, 2
MAN1A1	1.53	0.0021	Mannosidase, alpha, class 1A, member 1
MUC13	1.53	0.0038	Mucin 13, cell surface associated
CD164	1.52	0.0015	CD164 molecule, sialomucin
B4GALT5	1.51	0.0071	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5