Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis

doi:10.3748/wjg.v23.i37.6802

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Oct 7, 2017 (publication date) through Nov 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2017; 23(37): 6802-6816
Published online Oct 7, 2017. doi: 10.3748/wjg.v23.i37.6802

Table 6 Spearman correlations of ERα and ERβ expression in cytoplasmic tissue lysates with cytoplasmic pIKK

	r-coefficient (P value)
	Normal	HCV	HCC
Correlations with cytoplasmic ERα
Cytoplasmic ERβ	0.61233 (0.0599)	0.74376 (< 0.0001)^a	0.79765 (0.0158)^b
Cytoplasmic pIKK	-0.66837 (0.0346)^a	-0.00698 (0.9828)	-0.56014 (0.0194)^a
Correlations with cytoplasmic ERβ
Cytoplasmic ERα	0.61233 (0.0599)	0.91363 (< 0.0001)^b	0.79765 (0.0001)^b
Cytoplasmic pIKK	-0.60909 (0.0616)	-0.29717 (0.3482)	-0.60848 (0.0095)^a

^aP < 0.05,

^bP < 0.001. HCV: Hepatitis C virus; HCC: Hepatocellular carcinoma; ER: Estrogen receptor.

Citation: Iyer JK, Kalra M, Kaul A, Payton ME, Kaul R. Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis. World J Gastroenterol 2017; 23(37): 6802-6816
URL: https://www.wjgnet.com/1007-9327/full/v23/i37/6802.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i37.6802