Copyright
©The Author(s) 2017.
World J Gastroenterol. Oct 7, 2017; 23(37): 6750-6776
Published online Oct 7, 2017. doi: 10.3748/wjg.v23.i37.6750
Published online Oct 7, 2017. doi: 10.3748/wjg.v23.i37.6750
Table 1 Liver cancer stem cell markers in hepatocellular carcinoma
Marker | Another name | Function | Ref. |
CD133 | Prom-1 | Neurotensin/IL-8/CXCL1 signaling | [33,186] |
OV6 | Oval cell marker | Unknown until know, but it is considered to be an inducible progenitor cell marker in rodent models. | [8,38] |
EpCAM | Epithelial cell adhesion molecule | Activation of Wnt signaling | [187,188] |
CD13 | Cluster of differentiation 13 | ROS-induced DNA damage reduction | [71,72,189] |
CD24 | Heat-stable antigen | STAT3-mediated NANOG regulation | [18,34,150] |
CD90 | Thy-1 | Glycophosphatidylinositol (GPI) anchor | [18,32] |
CD44 | Hyaluronic acid receptor | Participation in epithelial mesenchymal transition | [33,69,190] |
ALDH | Aldehyde dehydrogenase | Group of intracellular enzymes that oxidize aldehydes (thereby serving a detoxifying role) | [15,39] |
- Citation: Flores-Téllez TN, Villa-Treviño S, Piña-Vázquez C. Road to stemness in hepatocellular carcinoma. World J Gastroenterol 2017; 23(37): 6750-6776
- URL: https://www.wjgnet.com/1007-9327/full/v23/i37/6750.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i37.6750