Serum angiotensin-converting enzyme level for evaluating significant fibrosis in chronic hepatitis B

Figure 5 Receiver operating characteristic curve analysis for diagnostic performance for predicting significant liver fibrosis. Compared to other markers, the area under curve (AUC) value in serum angiotensin-converting enzyme (ACE) level, 0.871, was higher than that in A: Aspartate aminotransferase to platelet index (APRI), 0.83 (P = 0.224); B: Fibrosis index based on the four factors (FIB-4), 0.641 (P = 0.0012); C: Serum levels of Mac-2 binding protein glycosylation isomer (M2BPGi), 0.717 (P = 0.0239); D: The number of platelets (Plt), 0.70 (P = 0.016).