Attenuation of MET-mediated migration and invasion in hepatocellular carcinoma cells by SOCS1

Figure 3 Reduced anchorage-independent proliferation of hepatocellular carcinoma cells expressing suppressor of cytokine signaling 1. SOCS1-expressing and control mouse Hepa (A) and human Hep3B and HepG2 (B) HCC cell lines were evaluated for their ability to form colonies in soft agar. After 3 wk culture, the colonies were photographed, and the number and size of colonies (area; mean ± SE) were evaluated from triplicates of two separate experiments. ^aP < 0.05. SOCS1: Suppressor of cytokine signaling 1.