Copyright
©The Author(s) 2017.
World J Gastroenterol. Sep 28, 2017; 23(36): 6674-6684
Published online Sep 28, 2017. doi: 10.3748/wjg.v23.i36.6674
Published online Sep 28, 2017. doi: 10.3748/wjg.v23.i36.6674
Table 2 Distribution of gene polymorphisms in patients with hepatocellular carcinoma, in hepatitis B/hepatitis C -positive patients, and in healthy controls n (%)
| Gene | SNP | Genotype | HCC group | HBV/HCV group | Healthy group |
| ERCC1 | rs3212986 | GG | 126 (67.7) | 82 (49.1) | 91 (47.4) |
| GT | 44 (23.7) | 78 (46.7) | 81 (42.2) | ||
| TT | 16 (8.6) | 7 (4.2) | 20 (10.4) | ||
| XRCC3 | rs1799794 | AA | 128 (66.7) | 108 (65.1) | 137 (71.7) |
| AG | 52 (27.1) | 55 (33.1) | 49 (25.7) | ||
| GG | 12 (6.3) | 3 (1.8) | 5 (2.6) | ||
| GST-P1 | rs1138272 | CC | 172 (92.5) | 139 (83.2) | 182 (94.8) |
| CT | 13 (7.0) | 27 (16.2) | 10 (5.2) | ||
| TT | 1 (0.5) | 1 (0.6) | 0 (0.0) | ||
| CYP17A1 | rs743572 | TT | 72 (38.1) | 39 (23.4) | 54 (28.4) |
| TC | 84 (44.4) | 88 (52.7) | 91 (47.9) | ||
| CC | 33 (17.5) | 40 (24.0) | 45 (23.7) | ||
| ABCB1 | rs1128503 | CC | 54 (28.1) | 52 (31.1) | 58 (30.2) |
| CT | 92 (47.9) | 93 (55.7) | 95 (49.5) | ||
| TT | 46 (24.0) | 22 (13.2) | 39 (20.3) |
- Citation: De Mattia E, Cecchin E, Polesel J, Bignucolo A, Roncato R, Lupo F, Crovatto M, Buonadonna A, Tiribelli C, Toffoli G. Genetic biomarkers for hepatocellular cancer risk in a caucasian population. World J Gastroenterol 2017; 23(36): 6674-6684
- URL: https://www.wjgnet.com/1007-9327/full/v23/i36/6674.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i36.6674