Changes of Ghrelin/GOAT axis and mTOR pathway in the hypothalamus after sleeve gastrectomy in obese type-2 diabetes rats

Figure 7 Changes of total ghrelin (A), acylated ghrelin (B) and acylated ghrelin/total ghrelin (C) at the first day, preoperatively and postoperatively. Statistical differences among the three groups at the same time point were analyzed by one-way ANOVA followed by the LSD-t test and between two time points in the same group using paired t test. ^aP < 0.05, preoperative or postoperative vs first day levels in the same group; ^cP < 0.05, postoperative vs preoperative levels in the SG group; ^eP < 0.05, SG vs S0 and Sh postoperatively. AG: Acylated ghrelin; TG: Total ghrelin; Sh: Sham operation group; SG: Sleeve gastrectomy; LSD: Least significant difference.